Tacrolimus
Tacrolimus, a wɔtɔn no Prograf din no mu no yɛ nnuru a ɛma nipadua no ho kwan yɛ mmerɛ. Berɛ a wɔasesa nipadua no nyinaa akyi no, asiane a ɛwɔ hɔ sɛ nipadua no bɛpo no yɛ ketewaa bi. Wɔde tacrolimus di dwuma na ama nkwammoaa a wɔtow wɔn gu no so atew. Wontumi ntɔ aduru no sɛ aduru a wɔde di dwuma wɔ baabi a ɛwo yare a T-cell na ɛwo no te sɛ eczema ne psoriasis. Sɛ nhwɛso no, wɔde ma obi a ɔyare uveitis a emu yɛ den bere a wɔasesa ne nnompe mu ntini, yare a ɛsakra no, Kimura yare, ne vitiligo. Wobɛtumi de asa ani ho yareɛ[1][2].
Tacrolimus siw calcineurin a ɛka interleukin-2 a ɛyɛ mmoawammoawa a ɛboa ma T- nkwammoaa nya nkɔso na ɛwo no ho kwan, a ɛyɛ nipadua no akwahosan ho mmuae a wɔasua (anaa nea ɛma ne ho yɛ den) no fã no kwan.
Wɔ ne mu no, ɛyɛ macrolide lactone a wɔhuu no wɔ afe 1987 mu, firii Japan asase a na mmoawa Streptomyces tsukubensis wɔ mu no mu. Ɛwɔ Wiase Nyinaa Akwahosan Ahyehyɛde no Akwankyerɛ a Ɛfa Aduru a Ɛho Hia ho. 10] Wɔ afe 2021 mu no, na ɛyɛ aduru a ɛtɔ so 296 a wɔtaa kyerɛw wɔ United States, a na wɔnkyerɛw no bɛboro 500,000[3][4].
Baabi a menyaa mmoa firiiɛ
sesa- ↑ Andrew Berdoulay, Robert V. English, Brad Nadelstein (2005-07), "Effect of topical 0.02% tacrolimus aqueous suspension on tear production in dogs with keratoconjunctivitis sicca", Veterinary Ophthalmology (in English), vol. 8, no. 4, pp. 225–232, doi:10.1111/j.1463-5224.2005.00390.x, ISSN 1463-5216, retrieved 2024-08-26
{{citation}}: Check date values in:|date=(help)CS1 maint: multiple names: authors list (link) - ↑ Tacrolimus for dogs and cats: Uses, Dosage & Side Effects (in English), retrieved 2024-08-26
- ↑ The Top 300 of 2022, retrieved 2024-08-26
- ↑ Tacrolimus - Drug Usage Statistics, ClinCalc DrugStats Database, retrieved 2024-08-26