Wɔatwerɛ nsɛm wei ɛwɔ Asante kasa mu
peptic ulcer disease
class of disease
subclass ofNsonomuyadeɛ, duodenal disease, Nyarewa, ulcer Sesa
has causeHelicobacter pylori infectious disease, non-steroidal anti-inflammatory drug Sesa
afflictsSTOM, duodenum Sesa
health specialtygastroenterology Sesa
symptoms and signsepigastric pain, heartburn, melena, hematemesis Sesa
ICD-9-CM533 Sesa
ICPC 2 IDD86 Sesa
NCI Thesaurus IDC3318 Sesa

Yamkuro yɛ nsisiiɛ a ɛsi yafunu nwoma no mu,ɔfa a ɛdi kan wɔ yafunu no mu a nnuanenuro kɔgu no, anaa sɛ drobɛn a ɛwɔ fam no.[1][2]Yamkuro a ɛsi wɔ yafunu mu no, wɔfrɛ no"gastric ulcer", na deɛ ɛsi wɔ yafunu no nwoma a ɛdi kan no, wɔfrɛ no "duodenal ulcer".[3]Yamkuro a ɛsi wɔ yafunu nwoma no mu a ɛnyɛ na koraa ne sɔre a wobɛsɔre anadwo ne w’ayase soro a ɛbɛyɛ wo ya na ɛrentumi mma wo nnidi no.[4]Wɔ kuro a ɛsi wɔ yafunu no mu no,yaw no ano bɛyɛ den na adidie nso bɛyɛ den.[5]Mpɛn pii no, wɔfrɛ saa yaw no sɛ ɔhyeɛ.Mpopoeɛ binom ne mmusoɔ,feɛ,wo so bɛte,anaa sɛ worentumi nnidi.Ɛbɛyɛ sɛ mpaninfoɔ nkyekyɛmu mmiɛnsa na sɛ wɔnya yamkuro a worenhunu ɛho mpopoeɛ.Nsunsuansoɔ no bi bɛtumi ayɛ mogyatuo,tokuro a ɛbɛsi wo yam anaa sɛ wo yam kwan bɛsi.Mogyatuo no si bɛyɛ ɔha mu nkyekyɛmu dunnum(15%)wɔ akwan beberee so.[6]

Deɛ Ɛde Ba

sesa

Adeɛ a ɛde yamkuro ba pa ara ne sɛ wobɛnya yareɛ a wɔfrɛ no Helicobacter pylori ne non-steroidal anti-inflammatory drugs(NSAIDS).[7]Nneɛma binom a ɛsan de yamkuro ba ne nnubɔnenom,sɛ wobɛha nipadua no beberee berɛ a nipadua no wɔ yareɛ bi a ano yɛ den no,nyarewa a ɛtumi bɔ nipadua akwaa beberee, yareɛ a ɛyɛ nipadua no mu deɛ ɛyam aduane a yɛdi kɔ yɛn mu no ne brɛboɔ ho yareɛ.[8]Wɔn a wɔanyini no wɔ atinka pa ara ma yamkuro a NSAIDS de ba no.[9]Wɔtumi hunu saa yamkuro yi ɛsiane mpopoeɛ a ɛda ne ho adi no a endoscopy anaa sɛ barium swallow de ba no.Yɛbɛtumi ahunu yareɛ a wɔfrɛ no H. Pylori sɛ yɛde mogya no fa mfidie mu hwehwɛ mmoawa a wɔbɔ nipadua no ho ban a,afei sɛ yɛbɛyɛ nhwehwɛmu afa dwonsɔtwaa ho,nhwehwɛmu a wode bɛhunu mmoawa binom,anaa sɛ yafunu no mu nhwehwɛmu. Nyarewa binom a ɛwɔ saa mpopoeɛ no bi ne yafunu yareɛ mu koankorɔ,akoma yareɛ, ne yafunu no nwoma a ɛno ara bɔ ne ho mmɔden tia nyarewa binom.[10]

Akwansideɛ

sesa

Adidie nnyɛ ade titire a ɛde yamkuro ba anaa sɛ ɛtumi si ayamtuo ano.[11]Ɛho ayaresa no bi ne sɛ wobɛgyae nnubɔnenom,wobɛgyae NSAIDS nom, wobɛgyae nsaden nom,na afei woanom nnuro a ɛbɛte nsuden a ɛwɔ yafunu no mu ahoɔden so.Mpɛn pii no nnuro a wɔde te saa nsuden yi ahoɔden so ne proton pump inhibitor(PPI) anaa sɛ H2 blocker, a ɛwɔ sɛ ɛho ayaresa no di nnawɔtwe nnan(4weeks).Wɔde nnuro ahodoɔ bi te sɛ amoxicillin, clarithromycin, ne PPI na ɛhwɛ yamkuro a H. Pylori de ba no.Nnuro ahodoɔ a ɛsi nyarewa ano kwan no kɔ soro deɛ nanso ɛnyɛ berɛ biara na ɛtumi di dwuma.Yɛbɛtumi de endoscopy asa yamkuro a ɛtu mogya,na yɛbɛtumi nso apae ne yam asa no yareɛ berɛ a endoscopy no antumi anyɛ adwuma no.[12]

Mpopoeɛ

sesa
 
 

Yamkuro ho mpopoeɛ na ɛdidisoɔ yi:[13]

  • Ayase yaw (abdominal pains) a wɔhyehyɛ no berɛ a wɔde didi.Sɛ ɛba no yamkuro a ɛsi wɔ yafunu nwoma no mu nso a, yaw no tumi di bɛyɛ dɔnhwere mmiɛnsa berɛ a nipa no adidi awie na wanyane no no.
  • Ayase hono(bloating)ne ayase yaw ankasa;
  • waterbrush(ntasuo a ɛfra nsuden wɔ drobɛn mu, ɛwɔ mu ɛne yareɛ a wɔfrɛ no gastroesophageal reflux disease na ɛnam);
  • Abofono ne feɛ ntɛntɛm
  • loss of appetite na afei wo so bɛte, wɔ yamkuro mu;
  • Wo mu bɛyɛ duru, wɔ yamkuro a ɛsi yafunu nwoma mu, a yaw no tumi gyae berɛ a woredidi no;
  • hematemesis(mogyafeɛ);deɛ ɛde ba ne moguatuo a ɛfiri yafunu no mu ba anaa sɛ, sɛ drobɛn no ho to kyema a, ɛsiane feɛ beberebe no nti.
  • melena(tarry, foul-smelling feces due to presence of oxidized iron from hemoglobin);
  • yamkuro tumi de tokuro to yafunu mu anaa yafunu nwoma mu, a ɛde honam mu kuro ba, yaw, a ɛhia sɛ yɛpae nipa no na yɛsa no yareɛ..

Nsɔano

sesa

Yamkuro nsɔano ma wɔn a wɔfa NSAIDS bɛtumi ayɛ yie sɛ wɔde nneɛma binom te sɛ proton pump inhibitor(PPI), H2 antagonist anaa sɛ misoprostol.[14]NSAIDS a ɛyɛ COX-2 inhibitors tumi te mpɛn dodoɔ a yamkuro de ba no so, sɛ wode toto non- selective NSAIDS no ho a.[15]PPI yɛ adeɛ a ɛtumi boa sɔ ayamkuro ano.Ɛkwan bi so no, yɛnni adanseɛ biara a ɛkyerɛ sɛ H2 antagonist tumi sɔ yafunu mu mogyatuo ano ma wɔn a wɔfa NSAIDS no.[16]Ɛwɔ mu misoprostol tumi boa si yamkuro ano,Wɔn a wɔwɔ cardiovascular risk a ɛwɔ soro no, naproxen a ɛwɔ PPI no hia pa ara. Ɛnte saa nso a, wobɛtumi de nnuro bi te sɛ aspirin, celecoxib, ne PPI kakra adi dwuma.

Abakɔsɛm

sesa

John Lykoudis, a ɔyɛ nhwehwɛmu fa nnwuma titire ho wɔ Greeceman mu no, de nnuro binom saa nnipa a ɔwɔ yamkuro yareɛ wɔ afe apem ahankron aduonum nwɔtwe(1958) mu, na ɛkyɛreeɛ pa ara ansa na wɔrehunu sɛ ɛyɛ mmoawa yi na ɛde ba.[17]

Ɛyɛ Robin Warren ne Barry J. Marshall a wɔyɛ abɔdeɛ mu nyansapɛfoɔ a wɔfiri Astraliaman mu hunu Helicobacter pylori sɛ ɛno ne adeɛ titire a ɛde ayamkuro ba, wɔ afe apem ahankron aduonwɔtwe mmienu(1982)mu. Wɔ wɔn krataa ankasa a wɔtwerɛeɛ no, Warren ne Marshall sii so dua sɛ yamkuro dodoɔ no ara no, ɛyɛ mmoawa yi na ɛde ba, na mmom no ɛnyɛ ɔbrɛ anaa sɛ nnuane binom a mfemfem nneɛma wɔ mu pii no na ɛde yamkuro ba, sɛdeɛ yɛsusu sɛ ɛteɛ no.[18]

Hyɛ No Nso

sesa

Ɛyɛ Sonnenberg, wɔ n'adesua mu no, ka sii no pi sɛ,ɛyɛ akwan ahodoɔ a wɔfa so de si yamkuro ano no, "sɛ wonom nsaden kakra a, ɛno nso tumi boa kum yamkuro".

Beaeɛ A Menyaa Mmoa Firiiɛ

sesa
  1. Wadie I. Najm (2011-09), "Peptic ulcer disease", Primary Care, vol. 38, no. 3, pp. 383–394, vii, doi:10.1016/j.pop.2011.05.001, ISSN 1558-299X, PMID 21872087, retrieved 2024-06-28 {{citation}}: Check date values in: |date= (help)
  2. Definition and Facts for Peptic Ulcer Disease, 2015-04-02, archived from the original on 2015-04-02, retrieved 2024-06-28
  3. Wadie I. Najm (2011-09), "Peptic ulcer disease", Primary Care, vol. 38, no. 3, pp. 383–394, vii, doi:10.1016/j.pop.2011.05.001, ISSN 1558-299X, PMID 21872087, retrieved 2024-06-28 {{citation}}: Check date values in: |date= (help)
  4. Wadie I. Najm (2011-09), "Peptic ulcer disease", Primary Care, vol. 38, no. 3, pp. 383–394, vii, doi:10.1016/j.pop.2011.05.001, ISSN 1558-299X, PMID 21872087, retrieved 2024-06-28 {{citation}}: Check date values in: |date= (help)
  5. S. Devaji Rao (2014-09-28), Clinical Manual of Surgery - e-book: Clinical Manual of Surgery - e-book (in English), Elsevier Health Sciences, ISBN 978-81-312-3871-4, retrieved 2024-06-28
  6. Tomica Milosavljevic, Mirjana Kostić-Milosavljević, Ivan Jovanović, Miodrag Krstić (2011), "Complications of peptic ulcer disease", Digestive Diseases (Basel, Switzerland), vol. 29, no. 5, pp. 491–493, doi:10.1159/000331517, ISSN 1421-9875, PMID 22095016, retrieved 2024-06-28{{citation}}: CS1 maint: multiple names: authors list (link)
  7. Tomica Milosavljevic, Mirjana Kostić-Milosavljević, Ivan Jovanović, Miodrag Krstić (2011), "Complications of peptic ulcer disease", Digestive Diseases (Basel, Switzerland), vol. 29, no. 5, pp. 491–493, doi:10.1159/000331517, ISSN 1421-9875, PMID 22095016, retrieved 2024-06-28{{citation}}: CS1 maint: multiple names: authors list (link)
  8. Wadie I. Najm (2011-09), "Peptic ulcer disease", Primary Care, vol. 38, no. 3, pp. 383–394, vii, doi:10.1016/j.pop.2011.05.001, ISSN 1558-299X, PMID 21872087, retrieved 2024-06-28 {{citation}}: Check date values in: |date= (help)
  9. Wadie I. Najm (2011-09), "Peptic ulcer disease", Primary Care, vol. 38, no. 3, pp. 383–394, vii, doi:10.1016/j.pop.2011.05.001, ISSN 1558-299X, PMID 21872087, retrieved 2024-06-28 {{citation}}: Check date values in: |date= (help)
  10. Wadie I. Najm (2011-09), "Peptic ulcer disease", Primary Care, vol. 38, no. 3, pp. 383–394, vii, doi:10.1016/j.pop.2011.05.001, ISSN 1558-299X, PMID 21872087, retrieved 2024-06-28 {{citation}}: Check date values in: |date= (help)
  11. Wadie I. Najm (2011-09), "Peptic ulcer disease", Primary Care, vol. 38, no. 3, pp. 383–394, vii, doi:10.1016/j.pop.2011.05.001, ISSN 1558-299X, PMID 21872087, retrieved 2024-06-28 {{citation}}: Check date values in: |date= (help)
  12. Tomica Milosavljevic, Mirjana Kostić-Milosavljević, Ivan Jovanović, Miodrag Krstić (2011), "Complications of peptic ulcer disease", Digestive Diseases (Basel, Switzerland), vol. 29, no. 5, pp. 491–493, doi:10.1159/000331517, ISSN 1421-9875, PMID 22095016, retrieved 2024-06-28{{citation}}: CS1 maint: multiple names: authors list (link)
  13. Symptoms & Causes of Peptic Ulcers (Stomach or Duodenal Ulcers) - NIDDK (in American English), retrieved 2024-06-28
  14. Angel Lanas, Francis K. L. Chan (2017-08-05), "Peptic ulcer disease", Lancet (London, England), vol. 390, no. 10094, pp. 613–624, doi:10.1016/S0140-6736(16)32404-7, ISSN 1474-547X, PMID 28242110, retrieved 2024-06-28
  15. Angel Lanas, Francis K. L. Chan (2017-08-05), "Peptic ulcer disease", Lancet (London, England), vol. 390, no. 10094, pp. 613–624, doi:10.1016/S0140-6736(16)32404-7, ISSN 1474-547X, PMID 28242110, retrieved 2024-06-28
  16. Angel Lanas, Francis K. L. Chan (2017-08-05), "Peptic ulcer disease", Lancet (London, England), vol. 390, no. 10094, pp. 613–624, doi:10.1016/S0140-6736(16)32404-7, ISSN 1474-547X, PMID 28242110, retrieved 2024-06-28
  17. Barry Marshall (2002-05-14), Helicobacter Pioneers: Firsthand Accounts from the Scientists who Discovered Helicobacters 1892 - 1982 (in English), Wiley, ISBN 978-0-86793-035-1, retrieved 2024-06-28
  18. B. J. Marshall, J. R. Warren (1984-06-16), "Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration", Lancet (London, England), vol. 1, no. 8390, pp. 1311–1315, doi:10.1016/s0140-6736(84)91816-6, ISSN 0140-6736, PMID 6145023, retrieved 2024-06-28