Pregabalin

pregabalin

type of chemical entity
subclass of	3-(Aminomethyl)-5-methylhexanoic acid
has use	aduro
stereoisomer of	CHEMBL167003
chemical formula	C₈H₁₇NO₂
canonical SMILES	CC(C)CC(CC(=O)O)CN
isomeric SMILES	CC(C)C[C@@H](CC(=O)O)CN
World Health Organisation international non-proprietary name	pregabalin
pregnancy category	Australian pregnancy category B3, US pregnancy category C
LiverTox likelihood score	LiverTox toxicity likelihood category C
subject has role	analgesic, anticonvulsant agent, calcium channel blocker, anxiolytic

Pregabalin din a wɔde nim no wɔ dwa so ne Lyrica. Ɛyɛ aduro a nneɛma bi te sɛ an anticonvulsant, analgesic, ne anxiolytic amino acid wɔ mu. Wɔde sa ɛtweɛ yadeɛ. Wɔtumi nso de sa nyarewa bi te sɛ adwenemu yaw( neuropathic pain), fibromyalgia, restless legs syndrome, opioid withdrawal, ne generalized anxiety disorder (GAD).^[1]^[2] Pregabalin alssan nso wɔ antiallodynic su.^[3]^[4]^[5]

Baabi a Menyaa Mmoa Firiiɛ

↑ Frampton JE (September 2014). "Pregabalin: a review of its use in adults with generalized anxiety disorder". CNS Drugs. 28 (9): 835–854. doi:10.1007/s40263-014-0192-0. PMID 25149863. S2CID 5349255.
↑ Iftikhar IH, Alghothani L, Trotti LM (December 2017). "Gabapentin enacarbil, pregabalin and rotigotine are equally effective in restless legs syndrome: a comparative meta-analysis". European Journal of Neurology. 24 (12): 1446–1456. doi:10.1111/ene.13449. PMID 28888061. S2CID 22262972.
↑ Wyllie E, Cascino GD, Gidal BE, Goodkin HP (February 17, 2012). Wyllie's Treatment of Epilepsy: Principles and Practice. Lippincott Williams & Wilkins. p. 423. ISBN 978-1-4511-5348-4.
↑ Kirsch D (October 10, 2013). Sleep Medicine in Neurology. John Wiley & Sons. p. 241. ISBN 978-1-118-76417-6.
↑ Frye M, Moore K (2009). "Gabapentin and Pregabalin". In Schatzberg AF, Nemeroff CB (eds.). The American Psychiatric Publishing Textbook of Psychopharmacology. pp. 767–77. doi:10.1176/appi.books.9781585623860.as38. ISBN 978-1-58562-309-9. Archived from the original on February 27, 2024. Retrieved September 1, 2022.

[pmid25149863-1] Frampton JE (September 2014). "Pregabalin: a review of its use in adults with generalized anxiety disorder". CNS Drugs. 28 (9): 835–854. doi:10.1007/s40263-014-0192-0. PMID 25149863. S2CID 5349255.

[pmid28888061-2] Iftikhar IH, Alghothani L, Trotti LM (December 2017). "Gabapentin enacarbil, pregabalin and rotigotine are equally effective in restless legs syndrome: a comparative meta-analysis". European Journal of Neurology. 24 (12): 1446–1456. doi:10.1111/ene.13449. PMID 28888061. S2CID 22262972.

[Wyllie_2012-3] Wyllie E, Cascino GD, Gidal BE, Goodkin HP (February 17, 2012). Wyllie's Treatment of Epilepsy: Principles and Practice. Lippincott Williams & Wilkins. p. 423. ISBN 978-1-4511-5348-4.

[Kirsch2013-4] Kirsch D (October 10, 2013). Sleep Medicine in Neurology. John Wiley & Sons. p. 241. ISBN 978-1-118-76417-6.

[SchatzbergNemeroff2009-5] Frye M, Moore K (2009). "Gabapentin and Pregabalin". In Schatzberg AF, Nemeroff CB (eds.). The American Psychiatric Publishing Textbook of Psychopharmacology. pp. 767–77. doi:10.1176/appi.books.9781585623860.as38. ISBN 978-1-58562-309-9. Archived from the original on February 27, 2024. Retrieved September 1, 2022.

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